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Manuel L Penichet Selected Research

Avidin

10/2015Efficacy of an Anti-transferrin Receptor 1 Antibody Against AIDS-related Non-Hodgkin Lymphoma: A Brief Communication.
1/2014Gene delivery in malignant B cells using the combination of lentiviruses conjugated to anti-transferrin receptor antibodies and an immunoglobulin promoter.
12/2007Binding specificity and internalization properties of an antibody-avidin fusion protein targeting the human transferrin receptor.
11/2007Conjugation of an anti transferrin receptor IgG3-avidin fusion protein with biotinylated saporin results in significant enhancement of its cytotoxicity against malignant hematopoietic cells.
8/2002An anti-transferrin receptor-avidin fusion protein exhibits both strong proapoptotic activity and the ability to deliver various molecules into cancer cells.

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Manuel L Penichet Research Topics

Disease

56Neoplasms (Cancer)
10/2022 - 08/2002
12Breast Neoplasms (Breast Cancer)
01/2019 - 03/2003
7Multiple Myeloma
01/2022 - 05/2007
6Carcinoma (Carcinomatosis)
10/2020 - 08/2002
5Glioma (Gliomas)
11/2020 - 10/2007
3Lymphoma (Lymphomas)
10/2022 - 01/2013
3Acquired Immunodeficiency Syndrome (AIDS)
01/2021 - 01/2013
3Hypersensitivity (Allergy)
01/2015 - 06/2009
3Hematologic Neoplasms (Hematological Malignancy)
11/2011 - 08/2002
2Brain Neoplasms (Brain Tumor)
01/2019 - 10/2007
2Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2019 - 10/2015
2Starvation
10/2015 - 05/2010
1Colonic Neoplasms (Colon Cancer)
10/2022
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
10/2022
1Infections
01/2022
1Pancreatic Neoplasms (Pancreatic Cancer)
12/2021
1Inflammation (Inflammations)
01/2021
1Viral Hemorrhagic Fevers (Viral Hemorrhagic Fever)
01/2020
1Virus Diseases (Viral Diseases)
01/2020
1Ulcer
01/2019
1HIV Infections (HIV Infection)
01/2019
1Noncommunicable Diseases
01/2018
1Paralysis (Palsy)
10/2016
1Prostatic Neoplasms (Prostate Cancer)
04/2013
1Anaphylaxis (Anaphylactic Shock)
04/2013
1Ascites
01/2013
1Ovarian Neoplasms (Ovarian Cancer)
07/2012
1American Hemorrhagic Fever (Bolivian Hemorrhagic Fever)
04/2012
1Fever (Fevers)
04/2012
1Cardiotoxicity
11/2011

Drug/Important Bio-Agent (IBA)

22Proteins (Proteins, Gene)FDA Link
01/2019 - 08/2002
18Transferrin Receptors (Transferrin Receptor)IBA
01/2022 - 08/2002
16Immunoglobulin G (IgG)IBA
01/2022 - 08/2002
13AntibodiesIBA
01/2021 - 01/2005
11AntigensIBA
12/2021 - 06/2005
7Immunoglobulin E (IgE)IBA
12/2021 - 06/2009
7CytokinesIBA
01/2019 - 01/2005
6Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
01/2019 - 03/2003
5Monoclonal AntibodiesIBA
10/2020 - 10/2007
5Interleukin-12 (IL 12)IBA
01/2019 - 03/2003
5VaccinesIBA
01/2018 - 03/2003
5AvidinIBA
10/2015 - 08/2002
5IronIBA
10/2015 - 11/2006
4Trastuzumab (Herceptin)FDA Link
01/2019 - 06/2009
3Immunoconjugates (Immunoconjugate)IBA
11/2020 - 01/2019
3Antisense OligonucleotidesIBA
11/2013 - 10/2007
3Interleukin-2 (IL2)IBA
11/2013 - 03/2003
3Pharmaceutical PreparationsIBA
02/2011 - 10/2007
2Proteasome InhibitorsIBA
10/2022 - 05/2008
2Neoplasm Antigens (Tumor Antigens)IBA
12/2021 - 09/2005
2malic acid (malate)IBA
01/2019 - 10/2007
2polycefinIBA
11/2013 - 10/2007
2poly(malic acid)IBA
11/2013 - 02/2011
2Oncogene Proteins (Oncogene Protein)IBA
11/2013 - 07/2012
2LigandsIBA
01/2013 - 11/2011
2ErbB-2 ReceptorIBA
02/2011 - 09/2005
2human ERBB2 proteinIBA
08/2010 - 06/2009
2Glycoproteins (Glycoprotein)IBA
11/2006 - 02/2006
1PiperidonesIBA
10/2022
1Ubiquitinated ProteinsIBA
10/2022
1pyrazoleIBA
06/2022
1Lenalidomide (CC 5013)FDA Link
01/2022
1Bortezomib (Velcade)FDA Link
01/2022
1OvalbuminIBA
12/2021
1Complement System Proteins (Complement)IBA
01/2021
1Protein Subunit VaccinesIBA
10/2020
1Immunoglobulin Fc FragmentsIBA
02/2020
1Dexamethasone (Maxidex)FDA LinkGeneric
02/2020
1Interferon Type IIBA
01/2020
1NestinIBA
01/2019
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2019
1Anti-Bacterial Agents (Antibiotics)IBA
01/2019
1PolymersIBA
01/2019
1Biopolymers (Biopolymer)IBA
01/2019
1Heparin (Liquaemin)FDA LinkGeneric
01/2019
1CTLA-4 AntigenIBA
01/2019
1Epidermal Growth Factor (EGF)IBA
01/2018
1Immunoglobulin Variable RegionIBA
01/2017
1Mechanistic Target of Rapamycin Complex 2IBA
10/2016
1Mechanistic Target of Rapamycin Complex 1IBA
10/2016
1DNA (Deoxyribonucleic Acid)IBA
01/2014
1DNA VaccinesIBA
01/2014
1Prostate-Specific Antigen (Semenogelase)IBA
04/2013
1Biological ProductsIBA
04/2013
1SaporinsIBA
02/2013
1Biomarkers (Surrogate Marker)IBA
01/2013
1Tumor Biomarkers (Tumor Markers)IBA
01/2013
1Chemokine ReceptorsIBA
01/2013
1Neutralizing AntibodiesIBA
01/2013
1EpitopesIBA
04/2012
1Peptides (Polypeptides)IBA
03/2012
1Vitamin EFDA LinkGeneric
11/2011
12,5,7,8- tetramethyl- 2R- (4R,8R,12- trimethyltridecyl)chroman- 6- yloxy acetic acidIBA
11/2011
1TeaIBA
11/2011
1alpha-TocopherolFDA Link
11/2011

Therapy/Procedure

27Therapeutics
01/2022 - 08/2002
12Immunotherapy
01/2022 - 01/2005
4Drug Therapy (Chemotherapy)
11/2011 - 02/2005
2Autologous Transplantation
07/2011 - 08/2002
1Combination Drug Therapy (Combination Chemotherapy)
10/2022